Abstract:

 Objective  To study the relationship between the grading of schistosomiasis japonica
hepatic lesions by B-ultrasonography and the portal vein and splenic vein haemodynamics. Methods
  The grades of 125 schistosomiasis patients' hepatic lesions were determined by Doppler ultra-
sonography according to the method recommended by WHO/TDR. The portal vein and splenic vein
inner diameters and blood flow velocity were examined and the portal vein and splenic vein volumes
of blood flow were calculated in the patients above mentioned and 51 normal persons. Results   The
inner diameters, blood flow velocity and volumes of blood flow of p.ortal vein and splenic vein in the
patients were significantly different from those in the normal persons, and also there were signifi-
cant differences among the patients with different degrees of fibrosis. Conclusions  The changes of
schistosomiasis patients' portal vein haemodynamics is connect with the liver parenchyma character-
istics. The step up of the ratio of blood flow volume of splenic vein with the portal vein is break-
down with the aggravate of the hepatic lesion.

Key words: Schistosomiasis, Hepatic lesion, Doppler ultrasonography, Portal vein, Splenicvein, Haemodynamics

摘要：

目的探讨血吸虫病肝损害程度B超分级与门静脉、脾静脉血流动力学的关系。方法采用彩色双功多普勒超声对125例血吸虫病患者按WHO/TDR推荐的方法进行肝纤维化程度分级，并检测患者及对照组51例正常人门静脉和脾静脉内径、血流速度，计算门静脉和脾静脉血流量。结果血吸虫病患者门静脉与脾静脉内径、血流速度、血流量与正常人比较差异有统计学意义；不同肝纤维化程度血吸虫病患者其门静脉与脾静脉内径、血流速度、血流量差异有统计学意义。结论血吸虫病患者门静脉血流动力学改变与其特征性病理改变有关；脾静脉血流量占门静脉血流量比例随肝纤维化程度加重逐渐升高。

关键词: 血吸虫病；肝损害；多普勒超声；门静脉；脾静脉；血流动力学