Chin J Schisto Control ›› 2007, Vol. 19 ›› Issue (3): 217-219.

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Analysis of factors on abnormal liver function in chronic schistosomiasis japonica patients

 |Chen Si-xi, Hou Xun-ya,Yan Fei-xiong   

  • Online:2013-01-15 Published:2013-01-21

慢性日本血吸虫病患者肝功能异常因素分析

陈四喜|侯循亚|颜飞雄   

  1. 湖南省血吸虫病防治研究所(岳阳414000)
  • 作者简介:陈四喜(1962-)|男|副主任医师。研究方向:血吸虫病防治

Abstract:

  Objective  To analyze the associated factors on abnormal liver function (LF) in
chronic schistosomiaisis japonica patients. Methods   The clinical data of 120 inpationts with chronic
schistosomiasis were collected and analyzed by logistic regression. The relevant treatment methods
were summarized. Results   The associated factors on abnormal LF of the patients were hepatitis B,
alcohol drinking, hyperlipidemia, nonalcoholic fatty liver disease (NAFLD), and obesity, respec-
tively. The ordinary medication for improving liver function was effective to these causes. Prazi-
quantal can be adnunistrated successfully to these patients after LF normalized. Conclusion
Chronic schistosomiasis patients with abnormal LF but without severe vital organ diseases could be
treated with praziquantal after their LF improving.

Key words:  Chronic schistosomiasis japonica, Liver function, Abnormality, Factors

摘要:

 目的分析慢性日本血吸虫病(慢血)患者肝功能异常的相关因素以其指导护肝和抗血吸虫治疗。方法收集120例慢血住院患者的临床资料,采用logistic回归法分析肝功能异常的相关因素,总结其护肝治疗方法。结果慢血伴肝功能异常的相关因素依次是乙型肝炎、血脂升高、饮酒、非酒精性脂肪肝、肥胖;其所致的转氨酶升高均可通过常规护肝治疗使肝功能恢复正常并顺利完成吡喹酮抗血吸虫治疗。结论在无器官功能严重损害的情况下,慢血伴肝功能异常经护肝治疗后不影响抗血吸虫的治疗。

关键词:  慢性日本血吸虫病;肝功能;异常因素

CLC Number: