Abstract: Objective Objective To explore the changing rule of schistosomiasis endemic situation in Gaoyou City，so as to provide the evidences for schistosomiasis control in lake and marshland regions. Methods Methods The endemic data of schistosomiasis of Gaoy? ou City from 1970 to 2009 were collected to analyze the endemic patterns of schistosomiasis in different control stages compre? hensively. Results Results In the first years of infection control stage（1970-1975），transmission control stage（1976-1994）and transmission interruption stage（1995-2009），the prevalence rates of schistosomiasis were 4.20%，0.80% and 0 in human and 3.00%，0.51% and 0 in cattle respectively. In 1984，the positive rate of crowd stool tests fell to 0.04%，which was reduced by 99.05% compared with that in 1970. From 1970 to 1980，the positive rates of stool tests of people and livestock were positively correlated significantly（r = 0.67，P < 0.05） . After 1985，no local infection patients or cattle were found. No schistosome infect? ed Oncomelania hupensis snails were found from 1970 to 2009. Conclusion Conclusion The comprehensive control measures have been insisted in Gaoyou City in different prevention and control stages. Although the snail situation is undulate，the prevalence of schistosomiasis steadily declines and the interruption of transmission has achieved.

Key words: Schistosomiasis；Oncomelania hupensis snail；Endemic situation；Gaoyou City

摘要： 目的 目的 探索高邮市血吸虫病疫情变化规律， 为湖沼型血吸虫病流行区防治工作提供科学依据。方法 方法 收集高 邮市1970-2009年血吸虫病防治工作数据， 对不同阶段血吸虫病防治与流行规律进行综合分析。 结果 结果 在血吸虫病疫 情控制 （1970-1975年）、 传播控制 （1976-1994年）、 传播阻断 （1995-2009年） 阶段的第1年， 人群血吸虫病粪检阳性率分 别为4.20%、 0.80%、 0， 牛粪检阳性率分别为3.00%、 0.51%、 0。1984年人群粪检阳性率下降至0.04%， 较1970年下降了 99.05%。1970-1980年人畜血吸虫粪检阳性率呈显著正相关 （r = 0.67， P < 0.05）。1985年后未查出当地感染的血吸虫病 人和病牛。1970-2009年均未查出血吸虫感染性钉螺。 结论 结论 高邮市在不同防治阶段坚持综合治理， 虽有螺情反复， 但 血吸虫病疫情稳定下降， 达到传播阻断标准。

关键词: 血吸虫病； 钉螺； 疫情； 高邮市