Abstract: Lysozyme generally exists in animals，plants and microorganisms，and it is used as a natural anti?infection materi? al and one of the important non?specific immune factors in organisms. This paper reviews the progress of researches on its classifi? cation，gene structure and function，and expression regulation in Oncomelania hupensis，and on the factors affecting its activi? ties in recent years，in order to further discuss its distribution in O. hupensis.

Key words: Oncomelania hupensis, Lysozyme, Gene expression, Cell location

摘要： 溶菌酶普遍存在于自然界动物、 植物、 微生物体内， 在动物体内可作为一种天然抗感染物质， 是生物体内重要的 非特异性免疫因子之一。本综述总结了近年来溶菌酶分类、 基因结构及功能、 在钉螺体内中的表达规律和影响溶菌酶活 性的因素， 为进一步探讨其在钉螺体内分布提供了基础资料。

关键词: 钉螺, 溶菌酶, 基因表达, 细胞定位