Abstract: Objective To explore the relationship between the hepatobiliary pathological changes under B?ultrasound examinations and Clonorchis sinensis infection， so as to provide the evidence for further prevention and control. Methods The stool test and ELISA were applied to test the pathogeny and antibody to C. sinensis of the suspicious patients who had the hepatobiliary pathological changes under B?ultrasound examinations in People’s Hospital of Wuxuan County from Jan. 2010 to Dec. 2013. Results Totally 113 suspicious patients of C. sinensis infection were investigated， and the positive rates of egg and serum antibody were 64.60% （73 cases） and 66.37% （75 cases） respectively. The positive rates of the male and those aged ≥ 50 years were significantly higher than those of the female and the cases younger than 50 years respectively （[χ2]= 3.554， 6.267， both P < 0.05）. In the C. sinensis infected patients， the degree of pathological changes of hepatobiliary was positively correlated with the infectiosity of C. sinensis （[χ2]= 64.952，P < 0.01）. Conclusion The hepatobiliary pathological changes under B?ultrasound examinations may be resulted from the infection of C. sinensis， and the patients with the changes should be further investigated for the pathogen and antibody to C. sinensis.

Key words: Clonorchiasis；Gallbladder； B?ultrasound scanning； Pathological change

摘要： 目的 探讨肝胆B超病理改变与华支睾吸虫感染的关系，为华支睾吸虫病诊断和治疗提供参考依据。 方法 对2010年1月至2013年12月，在武宣县人民医院行腹部B超检查发现的疑似华支睾吸虫感染者，采用粪检和酶联免疫法（ELISA）进行华支睾吸虫病原学和血清学检测。 结果 共检测疑似华支睾吸虫感染者113例，虫卵阳性率为64.60%（73例），血清抗体阳性率为66.37%（75例）。男性虫卵阳性率高于女性，50岁以上年龄组虫卵阳性率高于50岁以下组，差异均有统计学意义（[χ2]= 3.554、6.267，P均< 0.05）。感染者的肝胆B超病理改变程度与华支睾吸虫感染度呈正相关（[χ2]= 64.952，P < 0.01）。 结论 肝胆B超病理改变可能由华支睾吸虫感染引起，B超检查发现肝胆有病理改变者，应进一步进行华支睾吸虫病原学和血清学检测。

关键词: 华支睾吸虫病；胆囊；B超；病理改变