中国血吸虫病防治杂志 ›› 2019, Vol. 31 ›› Issue (2): 226-228.

• 病例报道 • 上一篇    

合肥市1例输入性卵形疟病例分析

王林*,李婷婷,汪清,李中良,刘漪   

  1. 安徽中医药大学第一附属医院检验中心(合肥 230031)
  • 出版日期:2019-05-24 发布日期:2019-05-26
  • 作者简介:王林,男,硕士,主管技师。研究方向:寄生虫病致病基因和机理研究

Imported Plasmodium ovale malaria in Hefei City: a case report

WANG Lin*, LI Ting-Ting, WANG Qing, LI Zhong-Liang, LIU Yi   

  1. Center of Clinical Laboratory, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China
  • Online:2019-05-24 Published:2019-05-26

摘要: 目的 对合肥市1例输入性卵形疟病例进行流行病学调查和实验室诊断分析,为今后预防控制输入性疟疾提供参考依据。方法 对该例输入性卵形疟患者的流行病学史、诊疗经过等资料进行收集、整理和分析。结果 患者从非洲莫桑比克务工返乡,回国数月后因反复发热就医。快速诊断试纸条法(RDT)提示为非恶性疟原虫感染;镜检见被感染红细胞正常大小或略胀大、锯齿状不明显,大滋养体胞浆增多、形态不规则、基本无空泡。荧光定量PCR确诊该病例为卵形疟原虫感染。结论 临床医务人员应加强对有境外流行区生活及工作史人员的疟疾诊断意识,及时早期合理用药,防止疟疾疫情扩散。

关键词: 卵型疟, 输入性病例, 镜检, 快速诊断试纸条法, 荧光定量PCR

Abstract: Objective To perform epidemiological survey and laboratory diagnosis of a Plasmodium ovale malaria case imported into Hefei City, so as to provide scientific evidence for the prevention and control of imported malaria in the future. Method The epidemiological history and clinical data of the imported malaria case were collected and analyzed. Results The patient returned to China from Mozambique, and was admitted to the hospital due to repeated fever several months after returning to China. Rapid diagnostic test (RDT) suggested non?P. falciparum infection, and microscopy displayed normal or slightly swelled malaria parasite?infected erythrocytes, unapparent serrated changes, increased cytoplasm in large trophozoite with irregular morphology, and almost no vacuoles. qPCR assay revealed P. ovale infection. Conclusions Clinical medical professionals should improve their awareness of malaria diagnosis in people with a history of living or working in overseas malaria?epidemic areas, and early and rational administration of antimalarials should be given promptly to prevent the spread of malaria epidemics.

Key words: Plasmodium ovale malaria, Imported case, Microscopy, Rapid diagnostic test, Fluorescent quantitative PCR

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