中国血吸虫病防治杂志 ›› 2019, Vol. 31 ›› Issue (2): 216-217,221.

• 防治经验 • 上一篇    下一篇

云南省边境地区人群弓形虫感染血清流行病学调查

李海龙1, 2,夏彬彬1,李倩1,张莉1, 2*   

  1. 1 大理大学基础医学院(大理 671000);2 云南省自然疫源性疾病防控技术重点实验室
  • 出版日期:2019-05-24 发布日期:2019-05-26
  • 通讯作者: 张莉
  • 作者简介:李海龙,男,博士,副教授。研究方向:病原生物学
  • 基金资助:
    国家自然科学基金(81560331、31760726)

Seroepidemiologic investigation of human Toxoplasma gondii infections in border areas of Yunnan Province, China

LI Hai-Long1, 2, XIA Bin-Bin1, LI Qian1, ZHANG Li1, 2*   

  1. 1 School of Basic Medicine, Dali University, Dali 671000, China; 2 Yunnan Provincial Key Laboratory of Zoonoses Control, China
  • Online:2019-05-24 Published:2019-05-26
  • Contact: ZHANG Li

摘要: 目的 了解云南省3个边境地区不同性别、年龄和民族的人群弓形虫感染状况,为该地区弓形虫病防控提供实验依据。方法 2015?11–2016?05在云南省中老、中越、中缅3个边境地区采集人群血样561份(中越边境222份、中老边境170份、中缅边境169份),应用酶联免疫吸附试验(ELISA)检测血清中抗弓形虫IgG抗体。结果 云南省边境地区人群抗弓形虫IgG抗体总阳性率为7.84%(44/561) ,其中中越、中老、中缅边境地区人群抗弓形虫IgG抗体阳性率分别为8.56%(19/222)、8.82%(15/170)和5.92%(10/169)。汉族、哈尼族、傣族、苗族、拉祜族、基诺族、瑶族、彝族居民血清抗弓形虫抗体阳性率分别为5.63%(16/284)、10.96%(8/73)、13.70%(10/73)、4.17%(2/48)、11.11%(1/9)、7.69%(1/13)、12.00%(3/25)和11.11%(3/27);少数民族居民血清抗弓形虫抗体总阳性率(10.11%,28/277)显著高于汉族([χ2] = 3.884,P < 0.05),傣族居民血清抗弓形虫抗体阳性率显著高于汉族([χ2] = 5.594,P < 0.05)。11 ~ 20岁年龄组人群血清抗弓形虫IgG抗体阳性率最高,为23.53%(4/17),显著高于0 ~ 10岁年龄组[4.23%(3/71)]([χ2] = 4.593,P < 0.05)和31 ~ 40岁年龄组[4.00%(3/75)]([χ2] = 4.997,P < 0.05)。结论 云南省边境地区人群存在不同程度弓形虫感染,少数民族居民感染率明显高于汉族,有必要加强对少数民族居民的弓形虫病防控健康宣教。

关键词: 刚地弓形虫, 血清流行病学, 云南省

Abstract: Objective To ascertain the prevalence of Toxoplasma gondii infection in different genders, ages, and ethnic populations of three border regions in Yunnan Province, China, in order to provide the basic data for prevention and control of toxoplasmosis in these areas. Methods A total of 561 serum samples were collected from the local hospitals of three border regions of Yunnan Province (222 serum samples from China?Vietnam border region, 170 serum samples from China?Laos border region, and 169 serum samples from China?Myanmar border region) from November 2015 to May 2016. The detection of IgG antibodies of T. gondii was performed by ELISA. Results In total, 44 (7.84%) of the 561 serum samples were anti?Toxoplasma IgG positive. The positive rates were 8.56% (19/222), 8.82% (15/170) and 5.92% (10/169) in China?Vietnam, China?Laos, and China?Myanmar border regions, respectively. The anti?Toxoplasma IgG positive rates were 5.63%(16/284) in Han, 10.96% (8/73) in Hani, 13.70% (10/73) in Dai, 4.17% (2/48) in Miao, 11.11% (1/9) in Lahu, 7.69% (1/13) in Jinuo, 12.00% (3/25) in Yao, and 11.11% (3/27) in Yi, respectively. The anti?Toxoplasma IgG positive rate in minorities was 10.11%, which was higher than that in Han significantly ([χ2] = 3.884, P < 0.05), and the positive rate in Dai was higher than that in Han significantly ([χ2] = 5.594, P < 0.05). The anti?Toxoplasma IgG positive rate in the 11-20?year age group was 23.53% (4/17), which was higher than that in the 0-10 [4.23% (3/71)] ([χ2] = 4.593, P < 0.05) and 31-40?year groups [4.00% (3/75)] ([χ2] = 4.997, P < 0.05). Conclusions There are different degrees of T. gondii infection in the human population in the border areas in Yunnan Province, and the risk of infection in ethnic minorities is higher than that in Han nationality. The prevention and control of toxoplasmosis should focus on the minority population.

Key words: Toxoplasma gondii, Seroepidemiology, Yunnan Province

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