关键词: 肝多房棘球蚴病, 胆囊相关并发症, 少年儿童, 影响因素, 青海省

Abstract: Objective To investigate the distribution characteristics of gallbladder diseases in children with hepatic alveolar echinococcosis， and to analyze the related factors for hepatic alveolar echinococcosis and gallbladder diseases. Methods The clinical data of hepatic alveolar echinococcosis patients under 18 years were collected in Qinghai Provincial People's Hospitalfrom January 2012 to December 2017， and the gallbladder?related complications in the surgically treated patients with hepatic alveolar echinococcosis were analyzed. Results The clinical data of 51 child patients with hepatic alveolar echinococcosis were collected and analyzed. According to the PNM classification criteria of WHO， P1， P2 and P3 in the 51 patients accounted for 37.25% （19/51）， 41.18% （21/51） and 19.60% （10/51）， respectively. According to the diagnostic criteria （WS 257-2006） of China for echinococcosis， the patients of infiltration type， calcification type and liquefaction cavitary type accounted for 66.67% （34/51）， 21.57% （11/51） and 11.76% （6/51）， respectively. Among the 51 patients， 78.43% （40/51） of the patients had clinical symptoms of biliary tract disease， and 58.82% （30/51） had gallbladder?related complications. The operations were performed on 40 patients， and 77.50%（31/40） of them had the postoperative complications. The results of binary multivariate logistic regression analysis showed that the clinical image classification， the liver segment distribution， size， location and number of lesions of hepatic alveolar echinococcosis were important correlative factors for the occurrence of gallbladder complications in hepatic alveolar echinococcosispatients. Conclusions The incidence of complications related to gallbladder diseasesis higher in the children with hepatic alveolar echinococcosis in Qinghai Province， and it has great influence on the operation mode and the occurrence and prognosis of postoperative complications. The early diagnosis and treatment of alveolar echinococcosis in children is particularly important.

Key words: Hepatic alveolar echinococcosis； Gallbladder related complication； Child； Influencing factor, Qinghai Province