关键词: 疟疾, 诊断, 快速诊断试纸条, 消除, 江苏省

Abstract: Objective To analyze the results of samples testing of Jiangsu Provincial Malaria Diagnostic Reference Laboratory in 2017， so as to provide the evidence for improving the malaria diagnostic performance in this province. Methods The samples of reported malaria cases in Jiangsu were collected by the provincial reference laboratory （PRL） in 2017. The microscopy and nucleic acid test were performed to confirm the infection of Plasmodium species of each case， while Plasmodium antigen tests （rapid diagnostic test， RDT） were performed as well. The detection results were analyzed among different areas and different species. Results Totally 242 malaria cases were reported and the samples were collected by PRL in 2017. A total of 239 cases were confirmed Plasmodium infections， including 163 cases of Plasmodium falciparum infection， 21 cases of P. vivax infection， 11 cases of P. malariae infection， 43 cases of P. ovale infection， and 1 case of P. falciparum and P. ovale mixed?infection. The diagnostic coincidence rate of reported malaria case in 13 prefectures with districts was all > 80%， and the total coincidence rate was 88.8%. The species diagnostic coincidence rates of P. falciparum， P. vivax， P. malariae， and P. ovale were 98.8%， 57.1%， 63.6%， and 81.4% respectively， and the detection rates by RDT to those four species infections were 95.7%， 85.0%， 63.6% and 79.1% respectively. Conclusions In 2017， the malaria diagnostic quality of medical technicians is generally high in Jiangsu Province. However， the diagnostic capacity is slightly different among different regions， and the ability to identify non? P. falciparum parasites remains to be improved. RDT is not ideal for the detection of non?P. falciparum infection. In the current stage of malaria elimination， the malaria diagnostic capacity of technicians in all the sectors should be strengthened and maintained.

Key words: Malaria, Diagnosis, Rapid diagnostic test, Elimination, Jiangsu Province