中国血吸虫病防治杂志 ›› 2018, Vol. 30 ›› Issue (6): 619-624.

• 论著 • 上一篇    下一篇

3种常用灭螺药大规模现场应用效果与费用评价

吴洪初1,马玉才2*,张正球3,唐恺4,杜广林5,张进3,王建5,朱道建4,左引萍4*   

  1. 1国家卫生健康委员会寄生虫病预防与控制技术重点实验室、江苏省寄生虫与媒介控制技术重点实验室、江苏省血吸虫病防治研究所(无锡214064); 2江苏省扬州市邗江区疾病预防控制中心;3江苏省仪征市疾病预防控制中心;4江苏省扬州市疾病预防控制中心;5江苏省扬州市人民政府血吸虫病地方病防治领导小组办公室
  • 出版日期:2019-03-02 发布日期:2019-03-05
  • 通讯作者: 马玉才,左引萍
  • 作者简介:吴洪初,男,主管医师。研究方向:寄生虫病预防与控制
  • 基金资助:
    国家科技支撑计划(2009BAI78B07);江苏省临床医学科技专项(BL2014021);江苏省扬州市重大科技示范项目(YZ2017064)

Effect and cost-effectiveness of three commonly used molluscicides in large-scale field application

WU Hong-Chu1, MA Yu-Cai2*, ZHANG Zheng-Qiu3, TANG Kai4, DU Guang-Ling5, ZHANG Jin3, WANG Jian5, ZHU Dao-Jian4, ZUO Yin-Ping4*   

  1. 1 Key Laboratory of National Health Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China; 2 Hanjiang District Center for Disease Control and Prevention, Yangzhou City, Jiangsu Province, China; 3 Yizheng Center for Disease Control and Prevention, Jiangsu Province, China; 4 Yangzhou Center for Disease Control and Prevention, Jiangsu Province, China; 5 Yangzhou Office of Leading Group for Schistosomiasis and Other Endemic Diseases Control, Jiangsu Province, China
  • Online:2019-03-02 Published:2019-03-05
  • Contact: MA Yu?Cai,ZUO Yin?Ping

摘要: 目的 评价4%螺威粉剂、50%杀螺胺乙醇胺盐可湿性粉剂和26%四聚·杀螺胺悬浮剂在大规模现场应用中的灭螺效果与费用,为科学制订钉螺控制对策与措施提供依据。方法 采用现场实验与平行比较相结合的方法,选择有螺江滩环境并分为4个实验区,其中3个灭螺实验区、1个空白对照区,每个实验区环境面积均为10 hm2。实验区分别施用4%螺威粉剂、50%杀螺胺乙醇胺盐可湿性粉剂和26%四聚·杀螺胺悬浮剂进行灭螺,每组分别进行3次灭螺、每次间隔1 d,每次灭螺后7 d进行灭螺效果调查。记录各实验组灭螺药物、人工、物料运输、油料消耗和机械损耗等费用。分析比较各药物灭螺费用、钉螺死亡率和钉螺密度、每100 m2环境钉螺死亡率每增加1%的灭螺费用,评价各药物的灭螺效果与费用。结果 灭螺1、2、3次后,4%螺威粉剂组钉螺校正死亡率分别为67.34%、76.55%和84.60%,50%杀螺胺乙醇胺盐可湿性粉剂组分别为64.71%、75.17%和83.89%,26%四聚·杀螺胺悬浮剂组分别为66.55%、76.27%和86.67%。随着灭螺次数的增加,各组药物灭螺效果均显著增高(c2 = 79.333、94.718、117.020,P均 < 0.01),3种药物灭螺相同次数后钉螺死亡率间差异均无统计学意义(c2 = 1.590、0.571、3.238,P均 > 0.05)。4%螺威粉剂、50%杀螺胺乙醇胺盐可湿性粉剂和26%四聚·杀螺胺悬浮剂灭螺1、2、3次后,钉螺密度分别较灭螺前下降69.82%~86.60%、68.66%~86.55%和71.89%~88.87%,各组药物灭螺3次后活螺密度降幅均 > 85%。4%螺威粉剂、50%杀螺胺乙醇胺盐可湿性粉剂和26%四聚·杀螺胺悬浮剂每100 m2的灭螺费用分别为19.57、11.97元和10.47元;灭螺1、2、3次每100 m2钉螺死亡率每增加1%的费用分别为0.30、2.08、2.38元,0.20、1.10、1.32元和0.17、1.04、0.97元,均以第1次灭螺的费用?效果最高。结论 4%螺威粉剂、50%杀螺胺乙醇胺盐可湿性粉剂和26%四聚·杀螺胺悬浮剂在江滩现场大规模应用的灭螺效果相近,但费用?效果随着灭螺次数的增加呈下降趋势。

关键词: 钉螺;4%螺威粉剂;50%杀螺胺乙醇胺盐可湿性粉剂;26%四聚·, 杀螺胺悬浮剂;灭螺效果;费用-效果

Abstract: Objective To evaluate the effect and cost?effectiveness of three commonly used molluscicides, 4% "Luo?wei"(tea?seed distilled saponins, TDS), 50% niclosamide ethanolamine salt wettable powder (NESWP), and 26% metaldehyde and niclosamide suspension concentrate (MNSC) in large?scale field application, so as to provide the references for formulating the strategy of snail control. Methods The field test and parallel comparison were implemented. A marshland with Oncomelania hupensis snails of the Yangtze River was divided into 4 parts (10 hm2) for the research, and three of them were experimental areas while the last one was a blank control area. The experimental areas were sprayed with 4% "Luo?wei", 50% NESWP and 26% MNSC respectively for 3 times and the interval was 1 week. Seven days after each spraying the effect of snail control was investigated, and the costs of molluscicides, labor, transportation, fuel consumption and mechanical loss were recorded. The cost of each molluscicide, snail mortality, snail density, and the cost of increasing 1% of snail mortality per 100 m2 were analyzed and compared. Results After the first, second and third spraying, the corrected snail mortality rates were 67.34%, 76.55% and 84.60% respectively in the 4% "Luo?wei" group; the corrected snail mortality rates were 64.71%, 75.17% and 83.89% respectively in the 50% NESWP group; the corrected snail mortality rates were 66.55%, 76.27% and 86.67% respectively in the 26% MNSC group. There was no significant difference among the 3 groups in the snail mortality at the same spraying time (c2 = 1.590, 0.571, 3.238, all P > 0.05). In addition, along with the increase of the spraying times, the snail mortality of each group was increased significantly compared to that of the control group (c2 = 79.333, 94.718, 117.020, all P < 0.01). After the first, second and third spraying, the reduction rates of snail density were 69.82%-86.60% in the 4% "Luo?wei" group, 68.66%-86.55% in the 50% NESWP group, and 71.89%-88.87% in the 26% MNSC group respectively. The decreasing amplitude of the snail density was more than 85% in all the experimental areas after 3 rounds of spraying molluscicide. The snail control costs per 100 hm2 were 19.57 Yuan, 11.97 Yuan and 10.47 Yuan in the 4% "Luo?wei" group, 50% NESWP group, and 26% MNSC group respectively. After the first, second and third spraying, the costs of increasing 1% of snail mortality per 100 m2 were 0.30 Yuan, 2.08 Yuan and 2.38 Yuan in the 4% "Luo?wei" group, 0.20 Yuan, 1.10 Yuan and 1.32 Yuan in the 50% NESWP group, and 0.17 Yuan, 1.04 Yuan and 0.97 Yuan in the 26% MNSC group respectively, and the cost?effectiveness was the highest at the first spraying in all the three groups. Conclusions The effects of the three molluscicides for snail control are similar, but the efficacy of snail control is reduced as the spraying time increases.

Key words: Oncomelania hupensis; 4% ", Luo?wei", ; 50% niclosamide ethanolamine salt wettable powder; 26% metaldehyde and niclosamide suspension concentrate; Molluscicidal effect; Cost?effectiveness

中图分类号: