中国血吸虫病防治杂志 ›› 2018, Vol. 30 ›› Issue (2): 161-164.

• 论著 • 上一篇    下一篇

藏区人群细粒棘球蚴病患病影响因素的病例对照研究

吴文婷|伍卫平*|官亚宜|韩帅|薛垂召|王旭|刘白雪   

  1. 中国疾病预防控制中心寄生虫病预防控制所、世界卫生组织热带病合作中心、科技部国家级热带病国际联合研究中心、国家卫生和计划生育委员会寄生虫病原与媒介生物学重点实验室(上海 200025)
  • 出版日期:2018-05-11 发布日期:2018-05-14
  • 通讯作者: 伍卫平
  • 作者简介:吴文婷|女|硕士研究生。研究方向:流行病与卫生统计学

A case-control study on risk factors of cystic echinococcosis in humans in Tibetan areas

WU Wen-ting| WU Wei-ping*|GUAN Ya-yi| HAN Shuai| XUE Chui-zhao| WANG Xu| LIU Bai-xue   

  1. National Institute of Parasitic Diseases| Chinese Center for Disease Control and Prevention; WHO Collaborative Center for Tropical Diseases; National Center for International Research on Tropical Diseases| Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology| National Health and Family Planning Commission of China| Shanghai 200025| China
  • Online:2018-05-11 Published:2018-05-14
  • Contact: WU Wei?ping

摘要: 目的 了解藏区人群细粒棘球蚴病患病的影响因素,为制定相关的防治策略提供依据。 方法 于2017年8-9月,在环境、海拔相似的西藏那曲县和四川石渠县共选择4个细粒棘球蚴病患病率较高的乡,采用1∶1病例对照的研究方法,通过入户问卷方式调查影响当地人群患细粒棘球蚴病的相关因素并进行统计分析。 结果 共调查了378人,病例组和对照组各189人。单因素分析发现,养狗年数(OR = 1.032,P < 0.05)、养狗数量(OR = 1.260, P < 0.05)、养狗方式(OR = 1.434,P < 0.05)、是否喂狗内脏(OR = 1.531,P < 0.05)、周围是否有流浪狗(OR = 1.946, P < 0.05)是患细粒棘球蚴病的危险因素。多因素分析中,是否喂狗内脏、周围是否有流浪狗、饮水来源等3个变量纳入了多因素回归模型。 结论 喂狗内脏、周围有流浪狗、饮用河水均是人群患棘球蚴病的危险因素。

关键词: 细粒棘球蚴病;影响因素;藏区;病例对照研究

Abstract: Objectives To understand the risk factors of cystic echinococcosis in Tibetan population, so as to provide the reference for development of prevention and control strategies. Methods Four cystic echinococcosis highly?prevalent townships were selected from Naqu County of Tibet and Shiqu County of Sichuan Province, which had similar environmental and altitude conditions, from August to September, 2017. Applying the 1∶1 case?control study, a household survey was conducted to investigate the risk factors of echinococcosis in humans. Results A total of 378 residents were investigated, of which the numbers of cases and non?cases were both 189. The univariate analysis showed that the years of keeping dogs (OR = 1.032, P < 0.05), the number of keeping dogs (OR = 1.260, P < 0.05), the way of raising dogs (OR = 1.434, P < 0.05), feeding with raw viscera (OR = 1.531, P < 0.05), and there being stray dogs around (OR = 1.946, P < 0.05) were the risk factors of echinococcosis. As a result of the multivariate logistic regression analysis, only three risk factors, feeding with raw viscera, there being stray dogs around, and drinking water resource, were included in the regression model. Conclusion Feeding with raw viscera, there being stray dogs around, and drinking water resource are the risk factors of echinococcosis in humans.

Key words: Cystic echinococcosis; Risk factor; Tibetan area; Case?control study

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