中国血吸虫病防治杂志 ›› 2016, Vol. 28 ›› Issue (6): 678-682.

• 论著 • 上一篇    下一篇

隐孢子虫实验室安全风险评估模型的建立

熊彦红1|向芳2|夏尚1|郑彬1*   

  1. 1中国疾病预防控制中心寄生虫病预防控制所、世界卫生组织热带病合作中心、卫生部寄生虫病原与媒介生物学重点实验室(上海200025);2上海市嘉定区疾病预防控制中心
  • 出版日期:2016-12-11 发布日期:2016-12-11
  • 通讯作者: 郑彬
  • 作者简介:熊彦红|女|硕士研究生|副研究员。研究方向:科技卫生、实验室生物安全
  • 基金资助:
    上海市卫生和计划生育委员会委级课题(20134430)

Establishment of a risk assessment model for laboratory biosafety of Cryptosporidium

XIONG Yan-hong1| XIANG Fang2| XIA Shang1| ZHENG Bin1*   

  1. 1 National Institute of Parasitic Diseases| Chinese Center for Disease Control and Prevention| Key Laboratory of Parasite and Vector Biology| Ministry of Health| WHO Collaborating Centre for Tropical Diseases| Shanghai 200025| China; 2 Jiading District Center for Disease Control and Prevention| Shanghai| China
  • Online:2016-12-11 Published:2016-12-11
  • Contact: ZHENG Bin

摘要:

目的 建立隐孢子虫实验室安全风险评估模型,为从事隐孢子虫相关操作的实验室人员做好安全工作和预防实验室内发生隐孢子虫感染提供依据。方法 通过查阅文献和德尔菲法确定隐孢子虫实验室感染发生的风险因素,然后通过模糊层次分析法确定风险因素的权重,建立隐孢子虫实验室安全风险评估模型。 结果 建立了隐孢子虫实验室安全风险评估模型,各风险指标中粪便样本处理发生隐孢子虫实验室感染的概率较高,且危害程度高,其发生可能性、危害程度的指标组合权重分别为0.111和0.107,属于高危风险因素。结论 本研究建立的隐孢子虫实验室安全风险评估模型具有可行性,可望为实验室人员做好相应防护措施、预防实验室内发生隐孢子虫感染发生提供依据。

关键词: 隐孢子虫;实验室安全;模糊层次分析法;多指标综合评分法

Abstract:

Objective To evaluate the risk assessment model of Cryptosporidium laboratory, so as to provide the basis for laboratory personnel engaging in the operation of Cryptosporidium. Methods Firstly, the risk factors of Cryptosporidium infection in laboratory were determined by the literature and Delphi, and then the weights of risk factors were determined by fuzzy analytic hierarchy process. A risk assessment model for laboratory biosafety of Cryptosporidium was established. Results Compared to the indexes, based on the risk assessment model, stool sample processing was the two steps in the laboratory with high risk of infection and high risk factors, with the combination weights of risk possibility and hazard rating were 0.111 and 0.107, respectively. Conclusion The risk assessment model established is feasible. It can be used to make some suggestions for the related laboratory staff.

Key words: Cryptosporidium; Laboratory biosafety; Fuzzy analytical hierarchy process; Multi?index integrated assessment method

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